Doug Hills, author of the how-to guide Manga Studio for Dummies, has been commissioned by the software publisher Smith Micro to create a set of tutorials on how to use Manga Studio 4. There are 12 for Manga Studio Debut, the entry-level version, and 11 for Manga Studio EX, the full package. This overview is a good place to start, since it demonstrates the user interface:
There’s also an EX Overview that explains what features it has that Debut doesn’t:
The entire set of tutorials can be found at the Content Paradise YouTube channel.